Depression Specialist

Annette A. Lusko, DO -  - Ketamine Infusion Therapy

Ketamine Integrative Medicine

Annette A. Lusko, DO

Ketamine Infusion Therapy & Addiction Specialist located in Gilbert, AZ

Depression affects over 16.1 million American adults, and as many as 50% of them have treatment-resistant depression that doesn’t respond to traditional treatments. At Ketamine Integrative Medicine in Gilbert, Arizona, Annette Lusko, DO, is committed to providing a solution that works and offers both oral ketamine and ketamine infusions as alternative treatments for depression. If you’re living with depression, call Ketamine Integrative Medicine or schedule a consultation online today to find out if ketamine can help you.

Depression Q & A

What is depression?

Depression is a prevalent mental health condition that causes a persistent, low, depressed mood. The disease affects your mood, how you think, and your behavior, which can have a severe impact on your ability to function in everyday life. 

For example, depression causes symptoms, including:

  • Feeling sad, worthless, or hopeless
  • Lost interest in previously enjoyed activities
  • Changes in appetite and sleep habits
  • Low energy or fatigue
  • Reduced concentration and decision-making skills
  • Thoughts of death or suicide

Your symptoms can range in severity but must last for two weeks or more for a clinical depression diagnosis.  

Depression is different from grief or sadness. It tends to last much longer and pervasive. While grief and sadness come in waves and subside, depression is always present and doesn’t go away. However, events that trigger grief and sadness can also trigger depression.

What causes depression?

A wide range of factors contributes to depression. In many cases, abnormalities in the neurotransmitters and receptors that regulate your mood contribute to depression. 

Additionally, if you have a family medical history of depression or other mental health conditions, you have an increased risk of developing the disease. 

Exposure to trauma, violence, neglect, and poverty can also increase your risk of developing depression.

How is depression treated?

Traditionally, depression is treated with a combination of antidepressant medication and therapy. However, up to 50% of patients with depression don’t find lasting relief of their symptoms with conventional treatments. 

At Ketamine Integrative Medicine, Dr. Lusko and her team offer oral ketamine and ketamine infusions as well as SPRAVATO™ prescriptions. to treat depression. Ketamine works differently than other antidepressants in the brain. 

Traditional antidepressants affect the way your brain produces and uses neurotransmitters like serotonin and dopamine and take time to build up in your system before they take effect. 

Ketamine has a more rapid effect on your mood as it stimulates NMDA and AMPA receptors in your brain, allowing glutamate to activate the connections and receptors in your brain that regulate mood.  

Spravato is a medication that you take at the same time as an antidepressant. It’s a nasal esketamine spray delivered in the comfortable Ketamine Integrative Medicine office. In studies, it had a positive effect on treatment resistant depression. 

If you have depression and traditional treatments haven’t restored your quality of life, call Ketamine Integrative Medicine or make an appointment online today to find out if ketamine is right for you.